Maxicircle architecture and evolutionary insights into Trypanosoma cruzi complex.

• Main Authors: Luisa Berná (Author), Gonzalo Greif (Author), Sebastián Pita (Author), Paula Faral-Tello (Author), Florencia Díaz-Viraqué (Author), Rita De Cássia Moreira De Souza (Author), Gustavo Adolfo Vallejo (Author), Fernando Alvarez-Valin (Author), Carlos Robello (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We sequenced maxicircles from T. cruzi strains representative of the species evolutionary diversity by using long-read sequencing, which allowed us to uncollapse their repetitive regions, finding that their real lengths range from 35 to 50 kb. T. cruzi maxicircles have a common architecture composed...