PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

• Main Authors: Zhixin Lei (Author), Qianying Liu (Author), Shuaike Yang (Author), Bing Yang (Author), Haseeb Khaliq (Author), Kun Li (Author), Saeed Ahmed (Author), Abdul Sajid (Author), Bingzhou Zhang (Author), Pin Chen (Author), Yinsheng Qiu (Author), Jiyue Cao (Author), Qigai He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aims of the present study were to establish optimal doses and provide an alternate COPD for florfenicol against Streptococcus suis based on pharmacokinetic-pharmacodynamic integration modeling. The recommended dose (30 mg/kg b.w.) were administered in healthy pigs through intramuscular and intra...