Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21

• Main Authors: Eun Kyung Kim (Author), Seung Hoon Lee (Author), Joo Yeon Jhun (Author), Jae Kyeong Byun (Author), Jeong Hee Jeong (Author), Seon-Young Lee (Author), Jae Kyung Kim (Author), Jong Young Choi (Author), Mi-La Cho (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity and its associated metabolic disorders are related to the onset of fatty liver and the balance of white adipose tissue (WAT) and brown adipose tissue (BAT). We hypothesized that metformin, an effective pharmacological treatment for type 2 diabetes, would inhibit white adipogenesis, fatty liv...