Model of Chronic Itch in Aged Mice: Beneficial Effects of Drugs Affecting Descending Modulatory Systems

• Main Authors: Go Kojima (Author), Eriko Komiya (Author), Kotaro Honda (Author), Takahide Kaneko (Author), Yasushi Suga (Author), Mitsutoshi Tominaga (Author), Kenji Takamori (Author)
• Format: Book
• Published: Medical Journals Sweden, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pruritus in the elderly, particularly those cases without skin dryness or other identifiable causes, makes treatment challenging due to the lack of evidence regarding the therapeutic effects of antipruritics. This study proposes an age-related alloknesis mouse model for an evaluation system for such...