PARP-1 genetic polymorphism associated with radiation sensitivity of non-small cell lung cancer

• Main Authors: Hetong Wang (Author), Haitao Xie (Author), Shuying Wang (Author), Jiaying Zhao (Author), Ya Gao (Author), Jun Chen (Author), Yuxia Zhao (Author), Genyan Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

About 70% of non-small cell lung cancer (NSCLC) patients require radiotherapy. However, due to the difference in radiation sensitivity, the treatment outcome may differ for the same pathology and choice of treatment. Poly (ADP-ribose) polymerase 1 (PARP-1) is a key gene responsible for DNA repair an...