Stathmin dynamics modulate the activity of eribulin in breast cancer cells

• Main Authors: Mikihiro Yoshie (Author), Akari Ishida (Author), Haruka Ohashi (Author), Nami Nakachi (Author), Mana Azumi (Author), Kazuhiro Tamura (Author)
• Format: Book
• Published: Wiley, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Stathmin, a phosphoprotein that modulates microtubule dynamics, is highly expressed in breast cancer cells. Eribulin, a microtubule‐depolymerizing agent, is used to treat patients with advanced breast cancer. However, the detailed mechanisms underlying the action of eribulin during microtub...