The Immunosuppressive Properties of Cyclo-[<i>D</i>-Pro-Pro-<i>β</i>³-HoPhe-Phe-] Tetrapeptide Selected from Stereochemical Variants of Cyclo-[Pro-Pro-<i>β</i>³-HoPhe-Phe-] Peptide

• Main Authors: Krzysztof Kaczmarek (Author), Jolanta Artym (Author), Joanna Bojarska (Author), Barbara Pacholczyk-Sienicka (Author), Joanna Waśko (Author), Ingrid Jelemenska (Author), Wojciech M. Wolf (Author), Martin Breza (Author), Michał Zimecki (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The anti-inflammatory, antiviral, and anti-cancer properties, as well as the mechanism of action of cyclo-[Pro-Pro-<i>β</i>³-HoPhe-Phe-] tetrapeptide (denoted as 4B8M), were recently described. The aim of this work was to synthesize and evaluate the immunosuppressi...