Infection parameters in the sand fly vector that predict transmission of Leishmania major.

• Main Authors: Lisa W Stamper (Author), Rachel L Patrick (Author), Michael P Fay (Author), Phillip G Lawyer (Author), Dia-Eldin A Elnaiem (Author), Nagila Secundino (Author), Alain Debrabant (Author), David L Sacks (Author), Nathan C Peters (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To identify parameters of Leishmania infection within a population of infected sand flies that reliably predict subsequent transmission to the mammalian host, we sampled groups of infected flies and compared infection intensity and degree of metacyclogenesis with the frequency of transmission. The p...