Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

• Main Authors: Kerry E. Poppenberg (Author), Kaiyu Jiang (Author), Michael K. Tso (Author), Kenneth V. Snyder (Author), Adnan H. Siddiqui (Author), John Kolega (Author), James N. Jarvis (Author), Hui Meng (Author), Vincent M. Tutino (Author)
• Format: Book
• Published: BMC, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathobiology remains poorly understood. We used Encyclop...