Pediatric growth patterns in youth‐onset type 2 diabetes mellitus: Implications for physiologically‐based pharmacokinetic models

• Main Authors: Chelsea M. Hosey (Author), Kelsee Halpin (Author), Valentina Shakhnovich (Author), Chengpeng Bi (Author), Brooke Sweeney (Author), Yun Yan (Author), J. Steven Leeder (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract An accurate understanding of the changes in height and weight of children with age is critical to the development of models predicting drug concentrations in children (i.e., physiologically‐based pharmacokinetic models). However, curves describing the growth of a typical population of child...