Possible association between a polymorphism of EPAS1 gene and persistent pulmonary hypertension of the newborn: a case-control study

• Main Authors: Narongsak Nakwan (Author), Surakameth Mahasirimongkol (Author), Nusara Satproedprai (Author), Tassamonwan Chaiyasung (Author), Punna Kunhapan (Author), Cheep Charoenlap (Author), Kamonnut Singkhamanan (Author), Chariyawan Charalsawadi (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To explore possible genes related to the development of persistent pulmonary hypertension of the newborn (PPHN). Methods: The authors identified 285 single nucleotide polymorphisms (SNPs) of 11 candidate genes (BMPR2, EPAS1, PDE3A, VEGFA, ENG, NOTCH3, SOD3, CPS1, ABCA3, ACVRL1, and SMAD9)...