Immunological response as a source to variability in drug metabolism and transport

• 主要な著者: Hege eChristensen (著者), Monica eHermann (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2012-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Through the last decades it has become increasingly evident that disease-states involving cytokines affect the pharmacokinetics of drugs through regulation of expression and activity of drug-metabolizing enzymes, and more recently also drug transporters. The clinical implication is however difficult...