Improved Therapeutic Delivery Targeting Clinically Relevant Orthotopic Human Pancreatic Tumors Engrafted in Immunocompromised Pigs Using Ultrasound-Induced Cavitation: A Pilot Study

• मुख्य लेखकों: Khan Mohammad Imran (लेखक), Benjamin Tintera (लेखक), Holly A. Morrison (लेखक), Juselyn D. Tupik (लेखक), Margaret A. Nagai-Singer (लेखक), Hannah Ivester (लेखक), McAlister Council-Troche (लेखक), Michael Edwards (लेखक), Sheryl Coutermarsh-Ott (लेखक), Christopher Byron (लेखक), Sherrie Clark-Deener (लेखक), Kyungjun Uh (लेखक), Kiho Lee (लेखक), Paul Boulos (लेखक), Cliff Rowe (लेखक), Christian Coviello (लेखक), Irving C. Allen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Pancreatic tumors can be resistant to drug penetration due to high interstitial fluid pressure, dense stroma, and disarrayed vasculature. Ultrasound-induced cavitation is an emerging technology that may overcome many of these limitations. Low-intensity ultrasound, coupled with co-administered cavita...