P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types

• Main Authors: Ponarulselvam Sekar (Author), George Hsiao (Author), Yuan-Shen Chen (Author), Wan-Wan Lin (Author), Chi-Ming Chan (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO₃) is an oxidative toxic agent, and its retinal toxicity has been used as the model of dry age-related macular degeneration (AM...