Association between Irisin, hs-CRP, and Metabolic Status in Children and Adolescents with Type 2 Diabetes Mellitus

• Main Authors: Leticia Elizondo-Montemayor (Author), Adrian M. Gonzalez-Gil (Author), Oscar Tamez-Rivera (Author), Carla Toledo-Salinas (Author), Mariana Peschard-Franco (Author), Nora A. Rodríguez-Gutiérrez (Author), Christian Silva-Platas (Author), Gerardo Garcia-Rivas (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Proinflammatory cytokines and the novel myokine irisin, a cleavage product of FNDC5, have been found to play a role in obesity and type 2 diabetes mellitus (T2DM). Irisin has been shown to increase browning of adipose tissue, thermogenesis, energy expenditure, and insulin sensitivity, yet its associ...