Induction of Mast Cell Accumulation by Tryptase via a Protease Activated Receptor-2 and ICAM-1 Dependent Mechanism

• Main Authors: Xin Liu (Author), Junling Wang (Author), Huiyun Zhang (Author), Mengmeng Zhan (Author), Hanqiu Chen (Author), Zeman Fang (Author), Chiyan Xu (Author), Huifang Chen (Author), Shaoheng He (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mast cells are primary effector cells of allergy, and recruitment of mast cells in involved tissue is one of the key events in allergic inflammation. Tryptase is the most abundant secretory product of mast cells, but little is known of its influence on mast cell accumulation. Using mouse peritoneal...