Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine

Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine

Abstract Background We previously showed that the autophagy inhibitor chloroquine (CQ) increases inflammatory cleaved caspase-1 activity in myocytes, and that caspase-1/11 is protective in sterile liver injury. However, the role of caspase-1/11 in the recovery of muscle from ischemia caused by perip...

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Main Authors: Ulka Sachdev (Author), Ricardo Ferrari (Author), Xiangdong Cui (Author), Abish Pius (Author), Amrita Sahu (Author), Michael Reynolds (Author), Hong Liao (Author), Ping Sun (Author), Sunita Shinde (Author), Fabrisia Ambrosio (Author), Sruti Shiva (Author), Patricia Loughran (Author), Melanie Scott (Author)
Format: Book
Published: BMC, 2020-07-01T00:00:00Z.
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