HOTAIR Accelerates Dyskinesia in a MPTP-Lesioned Mouse Model of PD via SSTR1 Methylation-Mediated ERK1/2 Axis

• Main Authors: Lijun Cai (Author), Li Tu (Author), Xiulin Yang (Author), Qian Zhang (Author), Tian Tian (Author), Rang Gu (Author), Xiang Qu (Author), Qian Wang (Author), Jinyong Tian (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Homeobox transcript antisense RNA (HOTAIR), has been associated with neuroprotective effects in Parkinson's disease (PD). However, the underlying mechanisms still remain unclear. Hence, this present study attempted to clarify the functional relevance of HOTAIR in PD. We established an in vivo m...