Trophoblast retrieval from the cervical canal to predict abnormal pregnancy early in gestation: a pilot study

• Main Authors: Xiaoke Yang (Author), Liuyezi Du (Author), Yue Li (Author), Lin Liang (Author), Linlin Ma (Author), Shaowei Wang (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The current detection of fetal chromosomal abnormalities by non-invasive prenatal testing (NIPT) mainly relies on the cell free DNA(cfDNA) in the maternal blood. However, a gestational age of less than 12 weeks or a high maternal BMI affects cfDNA fetal fraction and further the d...