The β3 adrenoceptor in proliferative retinopathies: "Cinderella" steps out of its family shadow

• Main Authors: Maurizio Cammalleri (Author), Rosario Amato (Author), Massimo Dal Monte (Author), Luca Filippi (Author), Paola Bagnoli (Author)
• Format: Knjiga
• Izdano: Elsevier, 2023-04-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

In the retina, hypoxic condition leads to overgrowing leaky vessels resulting in altered metabolic supply that may cause impaired visual function. Hypoxia-inducible factor-1 (HIF-1) is a central regulator of the retinal response to hypoxia by activating the transcription of numerous target genes, in...