The Mechanisms of Action of Interleukin-1 on Rabbit Intestinal Epithelial Cells

• Main Authors: Fadia R. Homaidan (Author), Liming Zhao (Author), Iman Chakroun (Author), Carla A. Martin (Author), Robert Burakoff (Author)
• Format: Book
• Published: Hindawi Limited, 1999-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-1 (IL-1) is an inflammatory mediator that increases Cl- secretion in intestinal epithelial cells. To identify the signal transduction pathway(s) involved in IL-1's action, cells were treated with IL-1 and the levels of cyclooxygenase (COX) enzymes, prostaglandin E2 (PGE2) and phosph...