Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini.

• Main Authors: Porntip Pinlaor (Author), Natthawut Kaewpitoon (Author), Thewarach Laha (Author), Banchob Sripa (Author), Sasithorn Kaewkes (Author), Maria E Morales (Author), Victoria H Mann (Author), Sandi K Parriott (Author), Sutas Suttiprapa (Author), Mark W Robinson (Author), Joyce To (Author), John P Dalton (Author), Alex Loukas (Author), Paul J Brindley (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contrib...