A First Metabolite Analysis of Norfolk Island Pine Resin and Its Hepatoprotective Potential to Alleviate Methotrexate (MTX)-Induced Hepatic Injury

• Main Authors: Sherouk Hussein Sweilam (Author), Dalia E. Ali (Author), Ahmed M. Atwa (Author), Ali M. Elgindy (Author), Aya M. Mustafa (Author), Manar M. Esmail (Author), Mahmoud Abdelrahman Alkabbani (Author), Mohamed Magdy Senna (Author), Riham A. El-Shiekh (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-induced liver injury (DILI) represents a significant clinical challenge characterized by hepatic dysfunction following exposure to diverse medications. Methotrexate (MTX) is a cornerstone in treating various cancers and autoimmune disorders. However, the clinical utility of MTX is overshadowed...