Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis

• Main Authors: Jongsung Hahn (Author), Youngkwon Jo (Author), So Hee Yoo (Author), Jaekyu Shin (Author), Yun Mi Yu (Author), Young-Mi Ah (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background: The use of opioid-gabapentinoid combinations has increased, raising several safety concerns. However, meta-analysis studies focusing on this issue are limited.Objective: To evaluate the risk of central nervous system (CNS) depression, gastrointestinal (GI) adverse events, and mortality o...