Modeling tumor size dynamics based on real‐world electronic health records and image data in advanced melanoma patients receiving immunotherapy

• Main Authors: Perrine Courlet (Author), Daniel Abler (Author), Monia Guidi (Author), Pascal Girard (Author), Federico Amato (Author), Naik Vietti Violi (Author), Matthieu Dietz (Author), Nicolas Guignard (Author), Alexandre Wicky (Author), Sofiya Latifyan (Author), Rita De Micheli (Author), Mario Jreige (Author), Clarisse Dromain (Author), Chantal Csajka (Author), John O. Prior (Author), Karthik Venkatakrishnan (Author), Olivier Michielin (Author), Michel A. Cuendet (Author), Nadia Terranova (Author)
• Format: Book
• Published: Wiley, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer therapy but only a fraction of patients benefits from this therapy. Model‐informed drug development can be used to assess prognostic and predictive clinical factors or biomarkers associated with treatment respo...