Chemoresistance in human ovarian cancer: the role of apoptotic regulators

• Main Authors: Thompson Winston E (Author), Yan Xiaojuan (Author), Jahani-Asl Arezu (Author), Leung Brendan (Author), Fraser Michael (Author), Tsang Benjamin K (Author)
• Format: Book
• Published: BMC, 2003-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Ovarian cancer is among the most lethal of all malignancies in women. While chemotherapy is the preferred treatment modality, chemoresistance severely limits treatment success. Recent evidence suggests that deregulation of key pro- and anti-apoptotic pathways is...