Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells

• Main Authors: Nabil A. Alhakamy (Author), Usama A. Fahmy (Author), Shaimaa M. Badr-Eldin (Author), Osama A. A. Ahmed (Author), Hani Z. Asfour (Author), Hibah M. Aldawsari (Author), Mardi M. Algandaby (Author), Basma G. Eid (Author), Ashraf B. Abdel-Naim (Author), Zuhier A. Awan (Author), Nabil K. Alruwaili (Author), Amir I. Mohamed (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Icariin (ICA) is a flavonol glycoside that has pleiotropic pharmacological actions. It has cytotoxic effects against ovarian cancer cells and increases their chemosensitivity to chemotherapeutic drugs. Phytosomes are identified for their potential in drug delivery of cytotoxic agents. Thus, the purp...