Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice

• Main Authors: Triveni Kodi (Author), Sharanya Praveen (Author), Sravan Kumar Paka (Author), Runali Sankhe (Author), Adarsh Gopinathan (Author), Nandakumar Krishnadas (Author), Anoop Kishore (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sickness behaviour, a set of behavioural changes associated with neuroinflammation, is expressed as decreased mobility and depressed behaviour. Activation of AMP-activated protein kinase (AMPK) is reported to regulate inflammation in conditions such as Alzheimer and traumatic brain injury. Metformin...