MicroRNAs and Their Therapeutic Potential for Human Diseases: Aberrant MicroRNA Expression in Alzheimer's Disease Brains

Abstract.: MicroRNAs (miRNAs) are a group of small noncoding RNAs that regulate translational repression of multiple target mRNAs. The miRNAs in a whole cell regulate greater than 30% of all protein-coding genes. The vast majority of presently identified miRNAs are expressed in the brain in a spatia...

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Autor principal: Jun-ichi Satoh (Author)
Formato: Livro
Publicado em: Elsevier, 2010-01-01T00:00:00Z.
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