Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis

• Main Authors: Toshihiro Inubushi (Author), Ayaka Fujiwara (Author), Takumi Hirose (Author), Gozo Aoyama (Author), Toshihiro Uchihashi (Author), Naoki Yoshida (Author), Yuki Shiraishi (Author), Yu Usami (Author), Hiroshi Kurosaka (Author), Satoru Toyosawa (Author), Susumu Tanaka (Author), Tetsuro Watabe (Author), Mikihiko Kogo (Author), Takashi Yamashiro (Author)
• Format: Book
• Published: The Company of Biologists, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cleft palate is one of the major congenital craniofacial birth defects. The etiology underlying the pathogenesis of cleft palate has yet to be fully elucidated. Dissociation of the medial edge epithelium (MEE) at the contacting region of palatal shelves and subsequent migration or apoptosis of MEE c...