Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data

• Main Authors: Qing Wang (Author), Vassiliki Kotoula (Author), Pei-Chen Hsu (Author), Kyriaki Papadopoulou (Author), Joshua W. K. Ho (Author), George Fountzilas (Author), Eleni Giannoulatou (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The application of next-generation sequencing in cancer has revealed the genomic landscape of many tumour types and is nowadays routinely used in research and clinical settings. Multiple algorithms have been developed to detect somatic variation from sequencing data using either...