Circulating Soluble ACE2 Plays an Independent Role to Protect against Vascular Damage in Diabetic Mice

• Main Authors: Chris Tikellis (Author), Gardner N. Robinson (Author), Carlos J. Rosado (Author), Duygu Batu (Author), Maria A. Zuniga-Gutierrez (Author), Raelene J. Pickering (Author), Merlin C. Thomas (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Circulating levels of soluble ACE2 are increased by diabetes. Although this increase is associated with the presence and severity of cardiovascular disease, the specific role of soluble ACE2 in atherogenesis is unclear. Previous studies suggested that, like circulating ACE, soluble ACE2 plays a limi...