Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca2+-Release Channels/Ryanodine Receptors

• Main Authors: Georgina B. Gurrola (Author), E. Michelle Capes (Author), Fernando Z. Zamudio (Author), Lourival D. Possani (Author), Héctor H. Valdivia (Author)
• Format: Book
• Published: MDPI AG, 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scorpion venoms are rich in ion channel-modifying peptides, which have proven to be invaluable probes of ion channel structure-function relationship. We previously isolated imperatoxin A (IpTxa), a 3.7 kDa peptide activator of Ca2+-release channels/ryanodine receptors (RyRs) [1,2,3] and founding mem...