Hexarelin Modulation of MAPK and PI3K/Akt Pathways in Neuro-2A Cells Inhibits Hydrogen Peroxide-Induced Apoptotic Toxicity

• Main Authors: Ramona Meanti (Author), Laura Rizzi (Author), Elena Bresciani (Author), Laura Molteni (Author), Vittorio Locatelli (Author), Silvia Coco (Author), Robert John Omeljaniuk (Author), Antonio Torsello (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hexarelin, a synthetic hexapeptide, exerts cyto-protective effects at the mitochondrial level in cardiac and skeletal muscles, both in vitro and in vivo, may also have important neuroprotective bioactivities. This study examined the inhibitory effects of hexarelin on hydrogen peroxide (H<sub>2...