Effect of presumptive co-trimoxazole prophylaxis on pneumococcal colonization rates, seroepidemiology and antibiotic resistance in Zambian infants: a longitudinal cohort study

• Main Authors: CJ Gill (Author), V Mwanakasale (Author), MP Fox (Author), R Chilengi (Author), M Tembo (Author), M Nsofwa (Author), V Chalwe (Author), L Mwananyanda (Author), D Mukwamataba (Author), B Malilwe (Author), D Champo (Author), WB Macleod (Author), DM Thea (Author), DH Hamer (Author)
• Format: Book
• Published: The World Health Organization, 2008-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE: To ascertain the microbiological consequences of WHO's recommendation for presumptive co-trimoxazole prophylaxis for infants with perinatal HIV exposure. METHODS: Using a longitudinal cohort design, we followed HIV-exposed and HIV-unexposed infants trimonthly for up to 18 months per...