IL-37 Gene Modification Enhances the Protective Effects of Mesenchymal Stromal Cells on Intestinal Ischemia Reperfusion Injury

• Main Authors: Dejun Kong (Author), Yonghao Hu (Author), Xiang Li (Author), Dingding Yu (Author), Hongyue Li (Author), Yiming Zhao (Author), Yafei Qin (Author), Wang Jin (Author), Baoren Zhang (Author), Bo Wang (Author), Hongda Wang (Author), Guangming Li (Author), Hao Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Ischemia reperfusion injury (IRI) is the major cause of intestinal damage in clinic. Although either mesenchymal stromal cells (MSCs) or interleukin 37 (IL-37) shows some beneficial roles to ameliorate IRI, their effects are limited. In this study, the preventative effects of IL-37 gene-...