Penetration Depth of Propylene Glycol, Sodium Fluorescein and Nile Red into the Skin Using Non-Invasive Two-Photon Excited FLIM

• Main Authors: Mohammad Alhibah (Author), Marius Kröger (Author), Sabine Schanzer (Author), Loris Busch (Author), Jürgen Lademann (Author), Ingeborg Beckers (Author), Martina C. Meinke (Author), Maxim E. Darvin (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The stratum corneum (<i>SC</i>) forms a strong barrier against topical drug delivery. Therefore, understanding the penetration depth and pathways into the <i>SC</i> is important for the efficiency of drug delivery and cosmetic safety. In this study, TPT-FLIM (two-photon tomog...