Synthesis and Biological Evaluation of a Radiolabeled PET (Positron Emission Tomography) Probe for Visualization of In Vivo α-Fucosidase Expression

• Główni autorzy: Jonathan Cotton (Autor), Chris Marc Goehring (Autor), Anna Kuehn (Autor), Andreas Maurer (Autor), Kerstin Fuchs (Autor), Bernd J. Pichler (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The acidic hydrolase α-fucosidase (AF) is a biomarker for maladies such as cancer and inflammation. The most advanced probes for α-fucosidase are unfortunately constrained to ex vivo or in vitro applications. The in vivo detection and quantification of AF using positron emission tomography would all...