Hybrid Molecules of Azithromycin with Chloramphenicol and Metronidazole: Synthesis and Study of Antibacterial Properties

• Main Authors: Inna A. Volynkina (Author), Elena N. Bychkova (Author), Anastasiia O. Karakchieva (Author), Alexander S. Tikhomirov (Author), George V. Zatonsky (Author), Svetlana E. Solovieva (Author), Maksim M. Martynov (Author), Natalia E. Grammatikova (Author), Andrey G. Tereshchenkov (Author), Alena Paleskava (Author), Andrey L. Konevega (Author), Petr V. Sergiev (Author), Olga A. Dontsova (Author), Ilya A. Osterman (Author), Andrey E. Shchekotikhin (Author), Anna N. Tevyashova (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The sustained rise of antimicrobial resistance (AMR) causes a strong need to develop new antibacterial agents. One of the methods for addressing the problem of antibiotic resistance is through the design of hybrid antibiotics. In this work, we proposed a synthetic route for the conjugation of an azi...