Cholesterol de novo biosynthesis: a promising target to overcome the resistance to aromatase inhibitors in postmenopausal patients with estrogen receptor-positive breast cancer

Aim: Cholesterol is an essential component of cell membranes and serves as a precursor for several bioactive molecules, including steroid hormones and isoprenoids. Generally supplied by the bloodstream, the de novo cholesterol biosynthesis is activated in response to an increased cell requirement du...

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Bibliographic Details
Main Authors: Danila Coradini (Author), Federico Ambrogi (Author)
Format: Book
Published: Open Exploration Publishing Inc., 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available