Association of a genetic polymorphism (-44 C/G SNP) in the human <it>DEFB1 </it>gene with expression and inducibility of multiple β-defensins in gingival keratinocytes

• Main Authors: Dommisch Henrik (Author), Hacker Beth M (Author), Fredericks L Page (Author), Kalus Andrea A (Author), Presland Richard B (Author), Kimball Janet R (Author), Dale Beverly A (Author)
• Format: Book
• Published: BMC, 2009-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Human β-defensins (hBDs) are antimicrobial peptides with a role in innate immune defense. Our laboratory previously showed that a single nucleotide polymorphism (SNP) in the 5' untranslated region of the hBD1 gene (<it>DEF...