Association of a genetic polymorphism (-44 C/G SNP) in the human <it>DEFB1 </it>gene with expression and inducibility of multiple β-defensins in gingival keratinocytes

• मुख्य लेखकों: Dommisch Henrik (लेखक), Hacker Beth M (लेखक), Fredericks L Page (लेखक), Kalus Andrea A (लेखक), Presland Richard B (लेखक), Kimball Janet R (लेखक), Dale Beverly A (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2009-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Human β-defensins (hBDs) are antimicrobial peptides with a role in innate immune defense. Our laboratory previously showed that a single nucleotide polymorphism (SNP) in the 5' untranslated region of the hBD1 gene (<it>DEF...