Regulation of Chemokine Production via Oxidative Pathway in HeLa Cells

• Main Authors: Shinichiro Kina (Author), Toshiyuki Nakasone (Author), Hiroyuki Takemoto (Author), Akira Matayoshi (Author), Shoko Makishi (Author), Nao Sunagawa (Author), Feixin Liang (Author), Thongsavanh Phonaphonh (Author), Hajime Sunakawa (Author)
• Format: Book
• Published: Hindawi Limited, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation is associated with disease progression and, by largely unknown mechanisms, has been said to drive oncogenesis. At inflamed sites, neutrophils deploy a potent antimicrobial arsenal that includes proteinases, antimicrobial peptides, and ROS. Reactive oxygen species (ROSs) induce chemokine...