Case Report: Cardiac Surgery and Combined Lipid-Lowering Drug Therapy for Homozygous Familial Hypercholesterolemia

• Main Authors: Mingxin Gao (Author), Wenyuan Yu (Author), Hui Hu (Author), Hongli Liu (Author), Kangjun Fan (Author), Chengxiong Gu (Author), Lvya Wang (Author), Yang Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Homozygous familial hypercholesterolemia (HoFH) is a rare, autosomal dominant, hereditary, metabolic disease. HoFH patients exhibit severe coronary stenosis and valvular disease, which may result in sudden death, even during adolescence. The challenges faced during surgery and the poor curative effe...