The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

• Main Authors: Eliana Toren (Author), Jessica D. Kepple (Author), Kristen V. Coutinho (Author), Samuel O. Poole (Author), Iztiba M. Deeba (Author), Tanya H. Pierre (Author), Yanping Liu (Author), Maigen M. Bethea (Author), Chad S. Hunter (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...