The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

• Үндсэн зохиолчид: Eliana Toren (Зохиогч), Jessica D. Kepple (Зохиогч), Kristen V. Coutinho (Зохиогч), Samuel O. Poole (Зохиогч), Iztiba M. Deeba (Зохиогч), Tanya H. Pierre (Зохиогч), Yanping Liu (Зохиогч), Maigen M. Bethea (Зохиогч), Chad S. Hunter (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2023-10-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Objective: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...