The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

• मुख्य लेखकों: Eliana Toren (लेखक), Jessica D. Kepple (लेखक), Kristen V. Coutinho (लेखक), Samuel O. Poole (लेखक), Iztiba M. Deeba (लेखक), Tanya H. Pierre (लेखक), Yanping Liu (लेखक), Maigen M. Bethea (लेखक), Chad S. Hunter (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...