The critical interaction between valproate sodium and warfarin: case report and review

• Main Authors: Chenguang Zhou (Author), Yi Sui (Author), Weijin Zhao (Author), Chunyao Dong (Author), Li Ren (Author), Pingmei Song (Author), Bing Xu (Author), Xiaohong Sun (Author)
• Format: Book
• Published: BMC, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Valproic acid (VPA) and warfarin are commonly prescribed for patients with epilepsy and concomitant atrial fibrillation (AF). When VPA and warfarin are prescribed together, clinically important interactions may occur. VPA may replace warfarin from the protein binding sites and re...