Identifying the prevalence of clinically actionable drug‐gene interactions in a health system biorepository to guide pharmacogenetics implementation services

• Main Authors: Amy L. Pasternak (Author), Kristen Ward (Author), Madison Irwin (Author), Carl Okerberg (Author), David Hayes (Author), Lars Fritsche (Author), Sebastian Zoellner (Author), Jessica Virzi (Author), Hae Mi Choe (Author), Vicki Ellingrod (Author)
• Formato: Livro
• Publicado em: Wiley, 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Understanding patterns of drug‐gene interactions (DGIs) is important for advancing the clinical implementation of pharmacogenetics (PGx) into routine practice. Prior studies have estimated the prevalence of DGIs, but few have confirmed DGIs in patients with known genotypes and prescriptions...