Foxp3 and IL-10 expression correlates with parasite burden in lesional tissues of post kala azar dermal leishmaniasis (PKDL) patients.

• Main Authors: Gajendra Kumar Katara (Author), Nasim Akhtar Ansari (Author), Sandeep Verma (Author), V Ramesh (Author), Poonam Salotra (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Post kala-azar dermal leishmaniasis (PKDL), a sequel to visceral leishamaniasis (VL) in 5-15% cases, constitutes a parasite reservoir important in disease transmission. The precise immunological cause of PKDL outcome remains obscure. However, overlapping counter regulatory responses with...