A novel thinking: DDR axis refines the classification of ccRCC with distinctive prognosis, multi omics landscape and management strategy

• Main Authors: Aimin Jiang (Author), Jiaao Song (Author), Xiao Fang (Author), Yu Fang (Author), Zheng Wang (Author), Bing Liu (Author), Zhenjie Wu (Author), Le Qu (Author), Peng Luo (Author), Linhui Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundDNA damage response and repair (DDR) related signatures play an important role in maintaining genome stability and other biological processes. It also affects the occurrence, development, and treatment of cancer. However, in renal cell carcinoma (RCC), especially clear cell renal carcinoma...