TNF-α Enhances the Therapeutic Effects of MenSC-Derived Small Extracellular Vesicles on Inflammatory Bowel Disease through Macrophage Polarization by miR-24-3p

• Main Authors: Huikang Xu (Author), Jiamin Fu (Author), Lijun Chen (Author), Sining Zhou (Author), Yangxin Fang (Author), Qi Zhang (Author), Xin Chen (Author), Li Yuan (Author), Yifei Li (Author), Zhenyu Xu (Author), Charlie Xiang (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human menstrual blood-derived mesenchymal stem cells (MenSCs) and their secreted small extracellular vesicles (EVs) had been proven to relieve inflammation, tissue damage, and fibrosis in various organs. The microenvironment induced by inflammatory cytokines can promote mesenchymal stem cells (MSCs)...