Multiseed liposomal drug delivery system using micelle gradient as driving force to improve amphiphilic drug retention and its anti-tumor efficacy

• Asıl Yazarlar: Wenli Zhang (Yazar), Caibin Li (Yazar), Ya Jin (Yazar), Xinyue Liu (Yazar), Zhiyu Wang (Yazar), John P. Shaw (Yazar), Bruce C. Baguley (Yazar), Zimei Wu (Yazar), Jianping Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

To improve drug retention in carriers for amphiphilic asulacrine (ASL), a novel active loading method using micelle gradient was developed to fabricate the ASL-loaded multiseed liposomes (ASL-ML). The empty ML were prepared by hydrating a thin film with empty micelles. Then the micelles in liposomal...